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. 2021 Sep 14;12:726354. doi: 10.3389/fphys.2021.726354

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Copyright © 2021 Selivanova, Gaynullina and Tarasova.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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T4-induced suppression of contractile responses of endothelium-denuded sural arteries to methoxamine persists in the presence of Src-kinase (PP2) and Rho-kinase (Y27632) inhibitors. Concentration-response relationships to methoxamine obtained after preincubation with T4 or vehicle in the presence of PP3 (A) (inactive analogue of PP2, 10 μM), PP2 (B) (10 μM), H₂O (C) (vehicle for Y27632), and Y27632 (D) (3 μM). Number in parentheses represents the number of animals. *p < 0.05 compared to respective control group (Repeated Measures ANOVA with Tukey’s post hoc test).