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Relative abundance plots of gut microbe-derived extracellular vesicles of early CRC (n = 62) and late CRC (n=8) (A) at the phylum, (B) family, and (C) genus levels. (D) Boxplots of alpha diversity indices comparing late CRC with early CRC in gut microbe-derived extracellular vesicles. **p < 0.01 and *p < 0.05. CRC; colorectal cancer, OTU; operational taxonomic unit.
