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. 2021 Sep 14;11:650026. doi: 10.3389/fonc.2021.650026

Table 1.

Taxa showing a significant different in the abundance between CRC with control in the gut microbiota.

Taxon t-statistic Unadjusted p-value Adjusted p-value Reference
Phylum Firmicutes      
 Family Clostridiaceae 1 -4.17 <0.001 0.002 (31)
  Genus Clostridium sensu stricto 1 -4.17 <0.001 0.004
 Family Family XIII -3.73 <0.001 0.004 (32)
  Genus Family XIII AD 3011 group -3.73 <0.001 0.008
 Family Erysipelotrichaceae -3.50 <0.001 0.016 (31)
  Genus Erysipelotrichaceae UCG-003 -3.50 0.001 0.042
  Genus Turicibacter -2.89 0.004 0.129 (31)
 Family Ruminococcaceae (31, 33)
  Genus Ruminococcus 1 -5.81 <0.001 0.004 (34, 35)
  Genus Ruminococcaceae UCG-013 -3.78 <0.001 0.004
  Genus Butyricicoccus -2.68 0.009 0.224 (36)
  Genus Subdoligranulum -2.59 0.012 0.286
 Family Lachnospiraceae (31, 34)
  Genus Blautia -4.27 <0.001 0.009 (35)
  Genus [Eubacterium] hallii group -3.82 <0.001 0.003 (37)
  Genus Lachnospiraceae NC2004 group -3.45 <0.001 0.003
  Genus [Eubacterium] ventriosum -3.08 0.004 0.117 (37)
  Genus [Ruminococcus] torques group -2.15 0.037 0.553
 Family Peptostreptococcaceae -2.80 0.008 0.128 (31, 33)
  Genus Romboutsia -3.15 0.002 0.071
  Genus Terrisporobacter -2.43 0.020 0.393
 Family Christensenellaceae -2.76 0.007 0.124 (31)
  Genus Christensenellaceae R-7 group -2.76 0.007 0.207
 Family Leuconostocaceae -2.77 0.008 0.124 (38)
  Genus Weissella -2.77 0.008 0.209
 Family Lactobacillaceae -2.37 0.022 0.234 (31)
  Genus Lactobacillus -2.37 0.022 0.405
Phylum Bacteriodetes 6.55 <0.001 <0.001
 Family Bacteroidaceae 5.26 <0.001 0.002
  Genus Bacteroides 5.26 <0.001 0.004 (34, 39)
 Family Marinifilaceae 2.69 0.009 0.128
  Genus Odoribacter 2.69 0.009 0.227 (31, 33, 34, 39)
 Family Rikenellaceae 2.47 0.015 0.185 (31)
  Genus Alistipes 2.47 0.015 0.325 (33, 34)
 Family Tannerellaceae 2.03 0.046 0.390
  Genus Parabacteroides 2.03 0.046 0.613 (34)
Phylum Actinobacteria -5.82 <0.001 <0.001
 Family Bifidobacteriaceae -5.93 <0.001 0.002 (31)
  Genus Bifidobacterium -5.93 <0.001 0.004 (34, 35)
 Family Eggerthellaceae -2.52 0.014 0.185
  Genus Eggerthella -2.52 0.014 0.321 (33)
 Family Actinomycetaceae -2.36 0.021 0.234
  Genus Actinomyces -2.36 0.021 0.405 (31)

The change of column (log2 fold) represents the multiplicative change in taxa abundance from CRC to control.

Negative numbers represent a trend of decreasing abundance in CRC group compared with control group.

The data (p < 0.05) was provied as bold values.