Fig. 2.

Best fit of the quantitative core-clock model to mRNA and protein circadian datasets in the mouse liver. a mRNA expression for core-clock elements in pmol/L. b Protein levels for core-clock elements in pmol/L. Model simulation (orange lines), experimental data used for calibration (black circles). Depicted are mean values (n = 2 biological replicates) ± SEM. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)