Table 1:
Prevalence estimates for positive anxiety and depression screens & 95% CI by instruments* and epilepsy status
| Diagnosis of Epilepsy | Seizure Free in Past 6 Months** | ||||||
|---|---|---|---|---|---|---|---|
| Instrument (positive values) | Overall (N = 422) |
No/Uncertain (N = 58) |
Yes (N = 364) |
Uncertain (N = 15) |
Yes (N = 188) |
No (N = 161) |
P Value*** |
|
GAD-7
(≥ 10) |
0.24 0.21–0.29 |
0.22 0.14–0.35 |
0.25 0.21–0.30 |
0.40 0.20–0.64 |
0.17 0.12–0.23 |
0.32 0.26–0.40 |
0.0011 |
|
GAD-2
(> 2) |
0.31 0.27–0.35 |
0.35 0.24–0.47 |
0.30 0.26–0.35 |
0.47 0.25–0.70 |
0.20 0.15–0.27 |
0.40 0.33–0.48 |
<0.0001 |
|
GAD-SI
(≥ 2) |
0.23 0.19–0.27 |
0.31 0.21–0.44 |
0.21 0.18–0.26 |
0.33 0.15–0.58 |
0.18 0.13–0.24 |
0.25 0.19–0.32 |
0.11 |
|
NDDI-E
(≥ 16) |
0.20 0.17–0.25 |
0.26 0.16–0.38 |
0.20 0.16–0.24 |
0.33 0.15–0.58 |
0.14 0.096–0.20 |
0.25 0.19–0.32 |
0.0094 |
|
NDDIE-2
(> 4) |
0.20 0.16–0.24 |
0.28 0.18–0.40 |
0.18 0.15–0.23 |
0.40 0.20–0.64 |
0.11 0.070–0.16 |
0.26 0.19–0.33 |
0.0004 |
Confidence interval, CI; Generalized Anxiety Disorder-7, GAD-7; Generalized Anxiety Disorder-2, GAD-2; Single-item GAD, GAD-SI; Neurological Disorders Depression Inventory-Epilepsy, NDDI-E; Neurological Disorders Depression Inventory Epilepsy-2, NDDIE-2
PHQ-2(Patient Health Questionnaire-2) omitted, as there was only 1 positive screen across 422 individuals and thus inclusion in this table would be uninformative.
Among those with diagnosis of epilepsy (N=364)
P values based on Fisher exact test for comparison of seizure free and non-seizure free subgroups; there were no significant differences when those with a diagnosis of epilepsy were compared to those without an epilepsy diagnosis