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miR-335 upregulation improves sepsis-induced cardiac function. Changes in (A) LVDP, (B) +dP/dt and (C) -dP/dt in Langendorff-perfused mice 6 h post-CLP. *P<0.05 vs. WT. n=5. miRNA/miR, micro RNA; LVDP, left ventricular development pressure; +dp/dt, maximum pressure increase rate; -dp/dt maximum pressure reduction rate; CLP, cecal ligation and puncture; WT, wild-type.
