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. 2021 Sep 28;2021(9):CD009790. doi: 10.1002/14651858.CD009790.pub2

Kofotolis 2006.

Study characteristics
Methods Study design: RCT
Setting: Greece, not specified
Exercise groups: 2
Comparison groups: 1
Participants Number of participants: 86 (E1 = 28, E2 = 28, C1 = 30)
Chronic LBP duration: Not specified (moderate)
Neurological/radicular symptoms: Some participants
Mean age (years): 42
Sex (female): 100%
Interventions Exercise Group 1 (E1): Alternating trunk flexion‐extension isometric contractions against resistance for 10 seconds, with no motion intended, 3 sets of 15 repetitions; type = core strengthening; duration = 4 weeks; dose = low; design = partially individualised; delivery = group; additional intervention = none
Exercise Group 2 (E2): Alternating concentric and eccentric contractions (5 seconds) for truck flexion and flexion‐extension exercises, 3 sets of 15 repetitions; type = core strengthening; duration = 4 weeks; dose = low; design = standardised; delivery = group; additional intervention = none
Comparison Group 1 (C1): Usual care/no treatment (control group: no intervention)
Outcomes Core outcomes reported: Pain (Borg Rate of Perceived Pain Scale); function (Oswestry Disability Index)
Follow‐up time periods available for syntheses: 4 weeks (short); 8 weeks (short); 13 weeks (moderate)
Notes Conflicts of interest: Not reported
Funding source: Not reported
Other: SDs imputed
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk The randomisation method was not adequately specified.
Allocation concealment (selection bias) High risk Not described
Blinding of participants and personnel (performance bias)
All outcomes High risk Not described
Blinding of care provider (performance bias) High risk Not described
Blinding of outcome assessment (detection bias)
All outcomes High risk Not described
Incomplete outcome data (attrition bias)
All outcomes Unclear risk Of the 108 subjects, a total of 86 subjects completed all training and testing measurements (Table 1).
Participants analysed in group allocated (attrition bias) High risk ITT not used
Selective reporting (reporting bias) Low risk Support for judgement was not available.
Groups similar at baseline (selection bias) Low risk The groups were homogeneous and showed nonsignificant differences in basic characteristics (Table 1).
Co‐interventions avoided or similar (performance bias) Unclear risk None of the subjects received additional physical therapy interventions during the study period.
Compliance acceptable in all groups (performance bias) Unclear risk Not described
Timing of outcome assessment similar in all groups (detection bias) Low risk Support for judgement was not available.