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. 2021 Sep 28;2021(9):CD009790. doi: 10.1002/14651858.CD009790.pub2

Manniche 1988.

Study characteristics
Methods Study design: RCT
Setting: Denmark, healthcare
Exercise groups: 3
Comparison groups: 0
Participants Number of participants: 105 (E1 = 33, E2 = 36, E3 = 36)
Chronic LBP duration: 780 weeks (long)
Neurological/radicular symptoms: No participants
Mean age (years): 45
Sex (female): 39%
Interventions Exercise Group 1 (E1): Intensive strengthening: trunk, back strengthening routine; type = core strengthening; duration = 12 weeks; dose = high; design = standardised; delivery = individual; additional intervention = not specified
Exercise Group 2 (E2): Back strengthening routine, similar to intensive less dose; type = core strengthening; duration = 12 weeks; dose = low; design = standardised; delivery = individual; additional intervention = not specified
Exercise Group 3 (E3): Isometric exercises for lumbar spine; type = strengthening; duration = 4 weeks; dose = low; design = standardised; delivery = not specified; additional intervention = electrotherapy
Outcomes Core outcomes reported: Pain (Visual Analogue Scale); function (Activities of Daily Living Scale)
Follow‐up time periods available for syntheses: 12 weeks (short); 39 weeks (moderate)
Notes Conflicts of interest: Not reported
Funding source: Danish Research Council and the Danish Health Foundation, Sygekassemcs Helsefond
Other: None
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Support for judgement is not available
Allocation concealment (selection bias) Low risk Support for judgement is not available
Blinding of participants and personnel (performance bias)
All outcomes High risk Support for judgement is not available
Blinding of care provider (performance bias) High risk Support for judgement is not available
Blinding of outcome assessment (detection bias)
All outcomes Low risk Support for judgement is not available
Incomplete outcome data (attrition bias)
All outcomes Low risk Support for judgement is not available
Participants analysed in group allocated (attrition bias) Low risk Support for judgement is not available
Selective reporting (reporting bias) Low risk Support for judgement is not available
Groups similar at baseline (selection bias) Low risk Support for judgement is not available
Co‐interventions avoided or similar (performance bias) Low risk Support for judgement is not available
Compliance acceptable in all groups (performance bias) High risk Support for judgement is not available
Timing of outcome assessment similar in all groups (detection bias) Low risk Support for judgement is not available