Table 2.

Dose adjustment of study drugs according to renal function

Creatinine clearance (mL/min)	Dose	Frequency
Temocillin (intravenous)
30–60	1 g	Every 12 hours
10–30	1 g	Every 24 hours
<10	500 mg–1 g	Every 24–48 hours
Meropenem (intravenous)
26–50	1 g	Every 12 hours
10–25	500 mg	Every 12 hours
<10	500 mg	Every 24 hours
Ertapenem (intravenous)
<30	1 g	Every 24 hours
<30	Not recommended
Ciprofloxacin (oral)
>60	500 mg	Every 12 hours
30–60	250–500 mg	Every 12 hours
<30	250–500 mg	Every 24 hours
Amoxicillin-clavulanic acid (oral)
10–30	500/150 mg	Every 12 hours
<10	500/125 mg	Every 24 hours
Trimethoprim-sulfamethoxazole (oral)
>30	160/800 mg	Every 12 hours
15–30	80/400 mg	Every 12 hours
<15	Not recommended	Not recommended