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. 2021 Sep 27;8(1):e001004. doi: 10.1136/bmjresp-2021-001004

Table 2.

Prevalence of symptoms of asthma, rhinitis and eczema for ISAAC (2003) and GAN (2019) studies with 95% CIs

Written questionnaire ISAAC 2003 GAN 2019 Dif.
n % (95% CI) n % (95% CI) P value
Asthma symptoms
 Wheeze ever 1134 37.6 (35.9 to 9.4) 303 12.7 (11.4 to 14.1) <0.001
 Wheeze in the past 12 months 535 17.8 (16.4 to 9.2) 156 6.5 (5.6 to 7.6) <0.001
 Four or more attacks of wheeze in the past 12 months 76 2.5 (2.0 to 3.1) 19 0.8 (0.4 to 1.1) <0.001
 Sleep disturbance from wheeze, one or more nights a week in the past 12 months 41 1.4 (1.0 to 1.8) 16 0.7 (0.3 to 1.0) 0.017
 Speech limited by wheeze in the past 12 months 89 3 (2.4 to 3.6) 60 2.5 (1.8 to 3.2) 0.413
 Asthma ever 207 6.9 (6.0 to 7.8) 110 4.6 (3.8 to 5.4) 0.001
 Wheeze during or after exercise in the past
 12 months
319 10.6 (9.5 to 11.7) 440 18.5 (16.9 to 20.0) <0.001
 Night cough in the past 12 months 233 7.7 (6.8 to 8.7) 670 28.2 (26.3 to 30.0) <0.001
 Doctor diagnosis of asthma 80 3.4 (2.6 to 4.0)
Rhinitis
 Nose symptoms ever 1446 48 (46.2 to 49.7) 1343 56.4 (54.4 to 58.4) <0.001
 Nose symptoms in the past 12 months 1102 36.6 (34.8 to 38.3) 1091 45.8 (43.8 to 47.8) <0.001
 Nose and eye symptoms in the past 12 months 697 23.1 (21.6 to 24.6) 664 27.9 (26.0 to 29.7) <0.001
 Nose symptoms affecting activities a lot in the past 12 months 26 0.9 (5.9 to 12.6) 100 4.2 (3.3 to 5.0) <0.001
 Rhinitis ever 282 11.8 (10.5 to 13.1)
 Doctor diagnosis of rhinitis 203 8.5 (7.4 to 9.6)
Eczema
 Rash ever 918 30.5 (28.8 to 32.1) 418 17.6 (16.0 to 19.0) <0.001
 Rash in the past 12 months 675 22.4 (20.9 to 23.9) 330 13.9 (12.4 to 15.2) <0.001
 Flexural symptoms 599 19.9 (18.5 to 21.3) 247 10.4 (9.1 to 12.1) <0.001
 Complete clearance of rash in the past 12 months 356 11.8 (10.7 to 13.0) 259 10.9 (9.6 to 12.1) 0.448
 Sleep disturbance from rash, one or more nights a week in the past 12 months 72 2.4 (1.9 to 3.0) 42 1.8 (1.2 to 2.2) 0.144
 Eczema ever 354 11.7 (10.6 to 12.9) 85 3.6 (2.8 to 4.3) <0.001
 Doctor diagnosis of eczema 53 2.2 (1.6 to 2.8)

Dif, Difference; GAN, Global Asthma Network; ISAAC, International Study of Asthma and Allergies in Childhood.