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. 2021 Sep 23;5:24705470211032208. doi: 10.1177/24705470211032208

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© The Author(s) 2021

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — (A) Results of moderated mediation model examining sex, estradiol, pro-inflammatory cytokines collected posttrauma (sum of natural log transforms of interleukin [IL]-6, IL-1 $β$ , tumor necrosis factor [TNF] and interferon-gamma [IFNγ]), and probability of being on a nonremitting posttraumatic stress disorder (PTSD) symptom trajectory. (B) Interpolation lines showing the interaction effect between estradiol level and pro-inflammatory cytokine sum in males (M; solid line) and females (F; dashed line). *p < 0.05, **p < 0.01.