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. Author manuscript; available in PMC: 2021 Sep 28.
Published in final edited form as: Cell Rep. 2021 May 11;35(6):109113. doi: 10.1016/j.celrep.2021.109113

Figure 6. VNA-recolonized SAVI mice have a reduction in bacterial reads compared with ESPF and control recolonized mice and an outgrowth of Bacteroidales not found in germ-free samples.

Figure 6.

Ten-week-old STING N153S (SAVI) mice were recolonized with stool from VNA-treated STING N153S animals or left germ-free, and stool was collected at 12 weeks.

(A) Bacterial family reads obtained from metagenomic sequencing of stool DNA from ESPF, control recolonized, VNA-recolonized, or germ-free STING N153S mice.

(B) Bacterial family relative abundance obtained from metagenomic sequencing of stool DNA from ESPF, control recolonized, VNA-recolonized, or germ-free STING N153S mice.

(C) Bacterial species reads obtained from metagenomic sequencing of stool DNA from VNA-recolonized or germ-free STING N153S mice.

(D) Bacterial species relative abundance obtained from metagenomic sequencing of stool DNA from VNA-recolonized or germ-free STING N153S mice. Species unique to VNA-recolonized samples are shown in boldface. Data represent samples collected from n = 3 mice per condition pooled from 2 independent experiments.