Table 2.

Seven most frequently mutated genes and their function

RefSeq ID (Locus tag)	No. of species	No. of lineages	Product	Function
WP_006389199.1 (AT699_RS06735)	3	10	DNA-binding transcriptional regulator AxyZ	Antibiotic resistance
WP_006227290.1 (AT699_RS01870)	2	5	NAD(P)/FAD-dependent oxidoreductase	Metabolic pathways
WP_013391523.1 (AT699_RS03490)	2	10	Penicillin-binding protein 2	Antibiotic resistance
WP_006392856.1 (AT699_RS03490)	2	9	ABC transporter substrate-binding protein	Transport
WP_006394390.1 (AT699_RS11865)	2	9	multidrug efflux RND transporter permease	Antibiotic resistance
WP_006387572.1 (AT699_RS22580)	2	8	Signal transduction histidine kinase	Two-component signalling
WP_006221301.1 (AT699_RS25090)	2	10	TonB-dependent hemin, ferrichrome receptor	Transport