Table 4–
Characteristics of Individuals With Resting Normoxia and Exercise Desaturation*
| p Value | ||||||
|---|---|---|---|---|---|---|
| Characteristics | Continuous Oxygen (n = 210) | Intermittent Oxygen (n = 182) | No Oxygen (n = 79) | Continuous vs Intermittent | Continuous vs None | Intermittent vs None |
| Age, yr | 65.5 ± 6.2 | 66.9 ± 5.9 | 66.2 ± 5.9 | 0.02 | 0.40 | 0.33 |
| Race | ||||||
| White | 202 (96.2) | 170 (61.5) | 75 (94.9) | 0.25 | 0.74 | 0.78 |
| Nonwhite | 8 (3.8) | 12 (6.6) | 4(5.1) | |||
| Gender | ||||||
| Female | 84 (40.0) | 70 (38.5) | 25 (31.7) | 0.84 | 0.22 | 0.33 |
| Male | 126 (60.0) | 112 (61.5) | 54 (68.4) | |||
| Pack-yr | 64.0 ± 27.1 | 62.0 ± 29.3 | 67.4 ± 36.2 | 0.49 | 0.39 | 0.21 |
| Income, $ | ||||||
| < 15,000 | 41 (19.5) | 33 (18.1) | 17 (21.5) | 0.12 | 0.93 | 0.71 |
| 15,000–29,999 | 74 (35.2) | 54 (29.7) | 24 (30.4) | |||
| 30,000–49,000 | 62 (29.5) | 54 (29.7) | 25 (31.7) | |||
| ≥ 50,000 | 29 (13.8) | 41 (22.5) | 13 (16.5) | |||
| Missing/no answer | 4 (1.9) | 0 (0.0) | 0 (0.0) | |||
| BM1, kg/m2 | 25.3 ± 3.8 | 24.5 ± 3.4 | 24.3 ± 3.1 | 0.03 | 0.05 | 0.77 |
| FEV1, L | 0.73 ± 0.22 | 0.77 ± 0.21 | 0.86 ± 0.28 | 0.03 | < 0.0001 | 0.004 |
| FEV1, % predicted | 25.1 ± 6.6 | 27.7 ± 6.8 | 28.3 ± 8.3 | 0.002 | 0.001 | 0.28 |
| FVC, L | 2.4 ± 0.78 | 2.5 ± 0.78 | 2.7 ± 0.84 | 0.17 | 0.005 | 0.08 |
| FVC, % predicted | 64.1 ± 14.3 | 68.0 ± 15.4 | 68.1 + 15.7 | 0.01 | 0.04 | 0.94 |
| TLC, L | 7.7 ± 1.6 | 7.7 ± 1.5 | 8.1 ± 1.6 | 0.68 | 0.06 | 0.10 |
| TLC, % predicted | 127.6 ± 15.5 | 129.1 ± 13.0 | 127.8 ± 12.9 | 0.31 | 0.90 | 0.48 |
| RV, L | 5.1 ± 1.2 | 5.0 ± 1.1 | 5.1 ± 1.2 | 0.40 | 0.95 | 0.47 |
| RV, % predicted | 228.2 ± 49.6 | 221.4 ± 43.7 | 221.7 ± 49.7 | 0.15 | 0.32 | 0.96 |
| IC, L | 1.6 ± 0.60 | 1.8 ± 0.56 | 1.9 ± 0.63 | 0.05 | 0.0002 | 0.02 |
| IC, % predicted | 58.8 ± 17.3 | 63.4 ± 16.4 | 66.1 ± 16.7 | 0.008 | 0.001 | 0.22 |
| Dlco, mL/min/mm Hg | 7.2 ± 3.4 | 8.3 ± 2.5 | 9.4 ± 3.7 | 0.49 | 0.32 | 0.58 |
| Dlco, % predicted | 25.4 ± 10.9 | 29.7 ± 7.9 | 28.8 ± 6.3 | 0.39 | 0.58 | 0.84 |
| 6-min walk distance, feet | 347.9 ± 87.8 | 395.3 ± 95.2 | 400.8 ± 100 | < 0.0001 | < 0.0001 | 0.67 |
| Maximum exercise, W | 36.7 ± 21.0 | 42.0 ± 19.8 | 45.1 ± 23.7 | 0.01 | 0.004 | 0.27 |
| UCSD-SOBQ | 68.2 ± 16.9 | 60.6 ± 16.8 | 57.7 ± 19.4 | < 0.0001 | < 0.0001 | 0.23 |
| QWB | 0.55 ± 0.12 | 0.59 ± 0.11 | 0.57 ±0.10 | 0.002 | 0.28 | 0.16 |
| SGRQ | ||||||
| Symptoms | 58.5 ± 20.0 | 53.5 ± 18.7 | 54.7 ± 18.8 | 0.01 | 0.15 | 0.64 |
| Activity | 81.9 ± 12.3 | 79.8 + 13.1 | 78.1 ± 13.7 | 0.10 | 0.02 | 0.35 |
| Impact | 39.6 ± 15.9 | 35.4 ± 15.2 | 35.9 ± 14.4 | 0.01 | 0.08 | 0.80 |
| Total | 55.6 ± 12.7 | 51.9 ± 12.0 | 51.9 ± 12.3 | 0.004 | 0.03 | 0.98 |
| mBODE score | ||||||
| 0–2 | 2 (1.0) | 6 (3.3) | 7 (8.9) | < 0.0001 | < 0.0001 | 0.30 |
| 3–4 | 55 (26.2) | 84 (46.2) | 33 (41.8) | |||
| 5–6 | 92 (43.8) | 66 (36.3) | 27 (34.2) | |||
| 7–10 | 61 (29.1) | 26 (14.3) | 12 (15.2) | |||
*
Date we presented as mean ± SD or No. See Table 3 for expansion of abbreviations and definitions.