Table 1.
Variables and parameters for autoimmune Hashimoto thyroiditis disease
| Variable and parameter | Definition | Unit |
|---|---|---|
| T(t) | Thyrocytes concentration | cells/mL |
| TH17(t) | TH17 lymphocytes concentration | cells/mL |
| TH1(t) | TH1 lymphocytes concentration | cells/mL |
| B(t) | Bacteria from gut microbiota | cfu/mL |
| α | Thyrocytes growth rate | % |
| β | Predation rate of TH1 lymphocytes on thyrocytes | % |
| γ | Induction rate to the cellular apoptosis process | % |
| β 1 | Thyrocytes mortality rate | % |
| β 2 | TH17 mortality rate lymphocyte predation rate over thyrocytes | % |
| β 3 | TH1 mortality rate lymphocyte predation rate over thyrocytes | % |
| Treg | Treg lymphocyte concentration | cells/mL |
| φ 1 | TH17 lymphocyte differentiation rate | % |
| φ 2 | TH1 lymphocyte differentiation rate | % |
| φ 3 | Maximum contribution rate of bacteria to TH17 lymphocyte | % |
| α 1 | Growth rate of bacteria from gut microbiota | % |
| K | Bacterial carrying capacity in the gastrointestinal tract | bacteria/mL |
Abbreviations: TH, T helper cell; Treg, regulatory T cell.