Fig. 1.

Flow diagrams of the whole-lesion histogram and texture analysis. a-c: Foreground and background seed points were manually drawn inside (green color) and outside (red color) on three reformatted diffusion-weighted imaging (DWI) images with b = 1500 s/mm². e-g: Three-dimensional segmentations were generated on the DWI images. d, h: Histograms of the T2weighted (T2W) images and apparent diffusion coefficient (ADC) maps that were generated