Table 2.

ACKR3-Venus expression in the adult mouse peripheral organs

	Female	Male
Digestive system
Stomach	+ +	+ +
Intestine	+ +	+ +
Liver	+	n.a
Pancreas	+ +	+ +
Colon	+ +	+ +
Reproductive system
Uterine Horn	+ +	n.a
Testes	n.a	+ +
Seminal vesicles	n.a	+ +
Lymphatic system
Spleen	+ + + +	+ + +
Thymus	+	+
Fat
White fat	+	+
Cardio-respiratory system
Heart	+	+
Lung	+ +	+ +
Urinary system
Kidney	+ + +	+

Amplified ACKR3-Venus expression was assessed in adult (P56-P72) animals. Thirteen Ackr3^Venus/Venus mouse organs were obtained from females and males. Tissues were immunostained to amplify the Venus tag. Expression in Ackr3^Venus/Venus were compared to any background staining observed in Ackr3^WT/WT (n = 3) (Additional file 1: Figure S4–S7) organs. The ACKR3 organ expression of Ackr3^Venus/Venus are ranked as follows: low (+), moderate (+ +), high (+ + +), very high (+ + + +) expression. This analysis was only qualitative, and no statistical analysis has been done