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. 2021 Sep 28;19:63. doi: 10.1186/s12962-021-00316-1

Table 2.

Comparison of mortality risks between patients admitted for first stroke with different comorbidity categories

Univariable analysis Multivariable analysis: Model 1 Multivariable analysis: Model 2
HR (95% CI) P value aHRa (95% CI) P value aHRa (95% CI) P value
In-hospital mortality
 None 1.00 1.00 1.00
 Moderate 1.53 (1.10–2.14) 0.013 1.48 (1.06–2.07) 0.022 1.51 (1.08–2.11) 0.016
 Severe 3.50 (2.42–5.07)  < 0.001 2.88 (1.98–4.17) < 0.001 2.88 (1.98–4.17) < 0.001
 Very severe 3.95 (2.78–5.62) < 0.001 3.84 (2.70–5.46) < 0.001 3.83 (2.70–5.45) < 0.001
7-day mortality
 None 1.00 1.00 1.00
 Moderate 1.24 (0.80–1.93) 0.330 1.48 (1.06–2.07) 0.448 1.22 (0.79–1.90) 0.369
 Severe 3.61 (2.52–5.78) < 0.001 2.88 (1.98–4.17) < 0.001 2.96 (1.84–4.76) < 0.001
 Very severe 3.77 (2.40–5.94) < 0.001 3.84 (2.70–5.46) < 0.001 3.51 (2.22–5.53) < 0.001

aHR adjusted hazard ratio, HR hazard ratio

aModel 1: aHR was calculated with adjustments for age and sex; Model 2: aHR was calculated with adjustments for age, sex, season, stroke type