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. 2021 Sep 28;19:63. doi: 10.1186/s12962-021-00316-1

Table 3.

Comparison of mortality risks between patients admitted for different stroke type with different comorbidity categories

Comorbidity burdena In-hospital Mortality 7-day Mortality
Univariable Analysis Multivariable Analysis Univariable Analysis Multivariable Analysis
HR (95% CI) P value aHR (95% CI) P value HR (95% CI) P value aHR (95% CI) P value
Ischemic stroke
 None 1.00 1.00 1.00
 Moderate 1.62 (1.14–2.30) 0.007 1.57 (1.11–2.23) 0.012 1.34 (0.84–2.13) 0.215 1.27 (0.80–2.02) 0.310
 Severe 3.38 (2.27–5.04) < 0.001 2.68 (1.79–4.00) < 0.001 3.51 (2.10–5.87) < 0.001 3.32 (2.02–5.45) < 0.001
 Very severe 3.95 (2.71–5.75) < 0.001 3.86 (2.65–5.61) < 0.001 3.59 (2.18–5.89) < 0.001 3.32 (2.02–5.45) < 0.001
Hemorrhagic stroke
 None 1 1 1.00 1.00
 Moderate 0.98 (0.26–3.70) 0.975 0.92 (0.24–3.49) 0.904 0.88 (0.18–4.38) 0.880 0.80 (0.16–4.00) 0.790
 Severe 3.91 (1.45–10.56) 0.007 3.97 (1.47–10.70) 0.006 3.49 (1.07–11.44) 0.039 3.51 (1.07–11.52) 0.038
 Very severe 3.88 (1.40–10.76) 0.009 3.95 (1.42–10.99) 0.008 4.78 (1.54–14.84) 0.007 4.88 (1.57–15.14) 0.006

aHR adjusted hazard ratio, HR hazard ratio

aFour categories of comorbidity were defined based on Charlson Comorbidity Index scores of 0 (none), 1 (moderate), 2 (severe), and 3 or more (very severe)