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. 2021 Sep 22;24(5):818. doi: 10.3892/mmr.2021.12458

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — miR-205-5p knockdown alleviates symptoms of OVA-induced AR. (A) miR-205-5p expression levels in the nasal mucosa. (B) Frequency of nose rubbing and sneezing within 15 min of the final challenge with OVA. (C) Pathological alterations in the nasal mucosa of AR mice (magnification, ×200 and ×400; scale bars, 100 and 50 µm). Arrows indicate the necrotic cells of the nasal mucosa. Data are presented as the mean ± SD (n=7). **P<0.01 vs. Sham; ^##P<0.01 vs. AR + NC. AR, allergic rhinitis; miR, microRNA; NC, negative control; OVA, ovalbumin.