Figure 3.

miR-205-5p knockdown decreases OVA-induced inflammatory response. (A) Levels of T-IgE and OVA-specific IgE in serum. (B) Number of inflammatory cells, including leukocytes, eosinophils, neutrophils, lymphocytes and macrophages in nasal lavage fluid. (C) Levels of IL-4, IL-5 and IL-13 in the nasal mucosa. Data are presented as the mean ± SD (n=7). *P<0.05, **P<0.01 vs. Sham; ^#P<0.05, ^##P<0.01 vs. AR + NC. AR, allergic rhinitis; miR, microRNA; NC, negative control; OVA, ovalbumin; T-IgE, total IgE; OVA-sIgE, ovalbumin-specific serum immunoglobulin E.