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. 2020 Jul 14;2020(8):CD013679. doi: 10.1002/14651858.CD013679

Summary of findings 3. Digital targeted client communication via mobile devices compared to digital non‐targeted client communication (pregnant and postpartum women) for improving maternal, neonatal, and child health.

Digital targeted client communication via mobile devices compared to digital non‐targeted client communication (pregnant and postpartum women) for improving maternal, neonatal, and child health
Patient or population: pregnant and postpartum women
Setting: community and healthcare settings
Intervention: digital targeted client communication via mobile devices
Comparison: digital non‐targeted client communication
Outcomes Anticipated absolute effects* (95% CI) Relative effect
(95% CI) № of participants
(studies) Certainty of the evidence
(GRADE) Comments
Risk with digital non‐targeted communication Risk with digital targeted client communication
Health status and well‐being – maternal mortality and morbidity No studies reported this outcome. (0 studies) The effect of the intervention on maternal morbidity and mortality is unknown as there was no direct evidence.
Health status and well‐being – neonatal mortality and morbidity No studies reported this outcome. (0 studies) The effect of the intervention on neonatal morbidity and mortality is unknown as there was no direct evidence.
Health behaviour change: breastfeeding No studies reported this outcome. (0 studies) The effect of the intervention on breastfeeding is unknown as there was no direct evidence.
Service utilisation – attendance antenatal care appointments (attendance for antenatal influenza vaccination) 310 per 1000 326 per 100 (220 to 490) RR 1.05 (0.71 to 1.58) 204 (1 RCT) ⊕⊕⊝⊝
Lowa,b The intervention may make little or no difference to attendance for antenatal influenza vaccination, but the CI includes both an increase and a decrease in attendance.
Service utilisation: intrapartum care – skilled attendant at birth
Follow‐up: at delivery
875 per 1000 875 per 1000 (604 to 1000) RR 1.00 (0.69 to 1.45) 16 (1 RCT) ⊕⊝⊝⊝
Very lowb,c We are uncertain of the effect of the intervention on the proportion of women having a skilled attendant at birth because the certainty of the evidence was very low.
Unintended consequences No studies reported this outcome. (0 studies) The effect of the intervention on unintended consequences is unknown as there was no direct evidence.
*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: confidence interval; RCT: randomised controlled trial; RR: risk ratio.
GRADE Working Group grades of evidenceHigh certainty: we are very confident that the true effect lies close to that of the estimate of the effect.
Moderate certainty: we are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different.
Low certainty: our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect.
Very low certainty: we have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect.

aDowngraded one level for imprecision: 95% confidence intervals that encompass a potential harmful effect and a potential beneficial effect of the intervention.
bDowngraded one level for risk of bias: trial at unclear risk of bias for several domains.
cDowngraded two levels for risk of bias: trial at unclear or high risk of bias across all domains.