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. 2021 Sep 28;14:508. doi: 10.1186/s13071-021-05021-9

Table 2.

Correlation between various risk/protective factors and severity of COVID-19

All Women Men Toxo-free Toxo-infected
Tau P Tau P Tau P Tau P Tau P
Sex 0.116 0.0002 na na na na 0.112 0.0017 0.095 0.1713
Age 0.093 0.0032 0.124 0.0010 0.025 0.6763 0.066 0.0654 0.137 0.0494
Size of place of residence 0.009 0.7815 −0.002 0.9575 0.039 0.5093 0.000 0.9895 0.065 0.3477
Toxoplasmosis 0.146 0.0000 0.150 0.0001 0.123 0.0376 na na na na
Borreliosis 0.094 0.0123 0.120 0.0088 0.030 0.6529 0.010 0.8146 0.212 0.0301
Rh-positivity 0.036 0.3097 0.035 0.3929 0.064 0.3950 0.022 0.5941 0.098 0.2112
A blood group 0.019 0.5892 0.000 0.9945 0.079 0.2715 0.032 0.4210 −0.052 0.4932
B blood group −0.008 0.8101 −0.010 0.7940 0.009 0.8991 0.012 0.7680 −0.069 0.3606
AB blood group 0.021 0.5371 0.093 0.0210 −0.160 0.0254 −0.002 0.9586 0.080 0.2909
O blood group −0.028 0.4278 −0.050 0.2142 0.031 0.6694 −0.043 0.2834 0.048 0.5260
Being overweight 0.104 0.0012 0.107 0.0052 0.116 0.0558 0.089 0.0147 0.140 0.0505
Diabetes 0.004 0.8922 −0.021 0.5777 0.038 0.5301 0.019 0.5929 −0.022 0.7602
Cardiovascular problems 0.063 0.0514 0.063 0.0985 0.075 0.2194 0.049 0.1762 0.170 0.0174
Asthma 0.052 0.1055 0.036 0.3496 0.094 0.1233 0.039 0.2815 0.133 0.0630
Chronic obstructive pulmonary disease 0.072 0.0252 0.073 0.0583 0.080 0.1853 0.013 0.7220 0.219 0.0022
Immunodeficiency 0.135 0.0000 0.141 0.0002 0.116 0.0558 0.160 0.0000 0.067 0.3472
Allergy −0.015 0.6453 −0.011 0.7829 −0.025 0.6809 −0.028 0.4376 0.025 0.7235
Autoimmunity 0.137 0.0004 0.146 0.0011 0.112 0.1590 0.074 0.0874 0.254 0.0048
Living alone 0.034 0.2794 0.092 0.0151 −0.061 0.2999 0.030 0.3960 0.073 0.2990
Tobacco smoking 0.061 0.0576 0.045 0.2454 0.090 0.1364 0.082 0.0239 0.006 0.9351
Marijuana consumption −0.001 0.9777 −0.082 0.0330 0.081 0.1800 0.057 0.1207 −0.195 0.0065
Daily alcohol consumption −0.039 0.2311 −0.094 0.0138 0.067 0.2677 −0.055 0.1279 0.035 0.6289
Frequent singing −0.032 0.3162 −0.060 0.1153 0.056 0.3553 −0.053 0.1459 −0.001 0.9861
Sport −0.092 0.0044 −0.112 0.0036 −0.056 0.3543 −0.116 0.0015 −0.028 0.6944
Cold water swimming −0.047 0.1447 −0.041 0.2851 −0.055 0.3614 −0.062 0.0883 −0.041 0.5691
Frequent use of sauna −0.036 0.3550 −0.040 0.3731 −0.037 0.6432 −0.009 0.8280 −0.177 0.0491
Vitamins and supplements −0.047 0.1425 −0.029 0.4437 −0.087 0.1499 −0.068 0.0628 0.034 0.6329
Wearing glasses −0.033 0.3244 0.005 0.9037 −0.131 0.0346 −0.003 0.9346 −0.069 0.3559
Current dog-keeping 0.004 0.9321 0.015 0.7737 −0.042 0.6694 0.049 0.3497 −0.120 0.2637
Current cat-keeping 0.107 0.0203 0.123 0.0194 0.058 0.5549 0.084 0.1052 0.153 0.1544

The table shows effect size and significance, i.e. partial Kendall Tau and P-values. The effect of sex was controlled for age and size of place of residence, the effect of age for sex and size of place of residence, and size of place of residence for sex and age; all other effects were controlled for all three covariates. Positive Tau indicates a more severe course of COVID in participants reporting the factor listed in the first column. The results in bold were significant after correction for multiple tests. In the smaller group of men, all factors lost their significance after correction for multiple tests, but observed Tau values showed that the effects in men were generally stronger than those in women