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Nitrosative stress inhibits DLD activity (measured as OD at 340 nm)
Dihydrolipoyl dehydrogenase (DLD) represents component #3 of the αKGDH complex, and is inhibited by S-nitrosylation by the NO donor S-nitrosocysteine (SNOC, 200 μM) in an in vitro activity assay. SNO-DLD: S-nitrosylated DLD. * p < 0.01 by two-tailed Student’s t-test.
