Reaction conditions for the functionalisation of aliphatic crown ethers with aromatic bases.

CE	N-aromatic base	Init.	Solv.	t (h)	T (°C)	Yield (%) [Prod]ref
3	2-Methylquinoline	FeSO4	DMSO	1	RT	70–90 [32] 65a
3	Quinoxaline	TiCl3	H2O	—	RT	— [29] 65b
3	2-Methylquinoline	TiCl3	H2O	—	RT	— [32] 65b
3	2,6-Lutidine	TiCl3	H2O	—	RT	— [32] 65b
3	4-Methylquinoline	TiCl3	H2O	—	RT	— [29] 65b
3	Quinoline	FeSO4	DMSO	0.5	RT	20 [19] 65c 30 [32] 65c
3	Quinoxaline	FeSO4	DMSO	0.5	RT	85 [29] 65c
3	2-Methylquinoline	FeSO4	DMSO	1	RT	65 [32] 65d
1	2-Methylquinoline	FeSO4	DMSO	1	RT	69 [30] 65d
2	2-Methylquinoline	FeSO4	DMSO	1	RT	65 [31] 65d
3	4-Methylquinoline	hν	EDC	23	40	71 [29] 66
2	4-Methylquinoline	hν	EDC	23	40	61 [28]66
3	Isoquinoline	hν	EDC	23	40	68 [29] 66
2	Isoquinoline	hν	EDC	23	40	61 [28] 66