Table 4.

Baseline characters of patients with early puberty

Parameters Median (IQR)	CPP (n=14)	PT (n=7)	PPP (n=10)	P trend	P CPP vs PT	P CPP vs PPP
Age at onset of puberty (in year)	3.25 (1.5-5.78)	1.2 (0.6-4.0)	3.25 (1.98-5.78)	0.078	0.052	0.666
Age of presentation (in year)	4.95 (2.93-6.6)	2.1 (1.3-4.8)	4.0 (2.88-6.25)	0.215	0.146	0.796
Female (percentage)	10 (71.4%)	7 (100%)	7 (70%)
SMR at presentation
A	1 (1-1)	1 (1-1)	1 (1-1.25)	0.367	0.48	0.358
P	1 (1-2.25)	1 (1-1)	2.5 (1.75-3.0)	0.006	0.08	0.047
B	3 (3-4)	3 (2-3)	1 (1-2)	0.002	0.272	0.002
SPL in cm	7.8 (6.4-8)	NA	8 (8-8)	0.119	NA	0.119
TV in mL	5.5 (4.25-6)	NA	3 (2-3)	0.031	NA	0.031
Height SDS	0.8 (0.23-1.9)	0.3 (−0.5-1.0)	1.4 (−0.8-2.28)	0.521	0.294	0.883
Bone age SDS	2.93 (2.09-6.68)	−0.6 (−0.68-0.3)	4.23 (2.17-6.9)	0.01	0.003	1
Left Ovarian Volume in mL	2.6 (0.68-4.05)	0.5 (0.31-0.84)	0.5 (0.1-54.0)	0.115	0.019	0.434
Right Ovarian Volume in mL	2.1 (1.23-4.60)	0.3 (0.29-0.98)	0.4 (0.08-60.0)	0.047	0.007	0.157
Average Ovarian Volume in mL	2.4 (0.76-4.29)	0.42 (0.30-0.71)	0.45 (0.09-57.0)	0.03	0.003	0.222
Uterine Volume in mL	6.65 (5.10-10.25)	1.6 (1.4-2.0)	1.1 (0.3-30)	0.653	0.001	0.143

SMR - Sexual Maturity Rating, A - Axillary hair stage, P - Pubic hair stage, B - Breast stage, SPL - Stretched penile length, TV - Testicular volume