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. 2021 May 31;10(12):e019051. doi: 10.1161/JAHA.120.019051

Table 3.

Clinical End Points and Echocardiographic Data After the Procedure in the Propensity Score–Matched Analysis for Nonobese and Morbidly Obese Cohort

Clinical End Points

BMI 18.5–29.9

(n=770)

BMI >35

(n=770)

P Value
In‐hospital mortality 26 (3.4) 28 (3.6) 0.782
In‐hospital or 30‐d mortality 28 (3.6) 35 (4.6) 0.368
Vascular complications
Major 33 (4.3) 51 (6.6) 0.043
Minor 80 (14.1) 61 (9.3) 0.009
Vascular complications femoral access only
Major 32 (4.7) 48 (7.2) 0.052
Minor 79 (16.1) 58 (10) 0.003
Major vascular complications femoral access only by closure type
Percutaneous closure device 22 (4.0) 39 (6.7) 0.046
Surgical cutdown technique 8 (9.3) 9 (15.0) 0.291
Bleeding
Life‐threatening bleeding 22 (2.9) 19 (2.5) 0.659
Major bleeding 37 (4.8) 44 (5.7) 0.421
Life‐threatening and major 59 (7.7) 63 (8.2) 0.706
Minor bleeding 66 (8.6) 55 (7.3) 0.353
AKI
Stage I 85 (13.7) 101 (14.8) 0.548
Stage II and III 24 (3.9) 25 (3.7) 0.859
Any stage 109 (17.5) 126 (18.5) 0.646
Coronary occlusion 5 (0.7) 4 (0.5) 0.738*
Periprocedural Stroke 11 (1.4) 12 (1.6) 0.831
Hospital‐acquired pneumonia 11 (1.57) 10 (1.33) 0.690
New permanent pacemaker implantation 91 (13) 108 (15.6) 0.158
Length of hospital stay, d 6 [5–9] 5 [3–8] <0.001
Post‐TAVR echocardiogram parameters within 30‐d after TAVR
Moderate‐severe post‐TAVR AR 38 (5.0) 18 (2.5) 0.009
Postprocedural mean aortic valve gradient (mm Hg) 8 [6–11] 10 [7–14] <0.001
Severe patient‐prosthesis mismatch 7 (1.1) 23 (3.5) 0.004
Device success 678 (88.1) 650 (84.4) 0.038
Echocardiogram parameters at 1‐y after TAVR
1 y mean aortic valve gradient (mm Hg) 8 [6–11] 10 [7–14] <0.001

Values are expressed as n (%) or median [IQR]. AKI indicates acute kidney injury; AR, aortic regurgitation; BMI, body mass index; and TAVR, transcatheter aortic valve replacement.

*

Fisher’s exact test used.