Table 3.
Clinical End Points and Echocardiographic Data After the Procedure in the Propensity Score–Matched Analysis for Nonobese and Morbidly Obese Cohort
Clinical End Points |
BMI 18.5–29.9 (n=770) |
BMI >35 (n=770) |
P Value |
---|---|---|---|
In‐hospital mortality | 26 (3.4) | 28 (3.6) | 0.782 |
In‐hospital or 30‐d mortality | 28 (3.6) | 35 (4.6) | 0.368 |
Vascular complications | |||
Major | 33 (4.3) | 51 (6.6) | 0.043 |
Minor | 80 (14.1) | 61 (9.3) | 0.009 |
Vascular complications femoral access only | |||
Major | 32 (4.7) | 48 (7.2) | 0.052 |
Minor | 79 (16.1) | 58 (10) | 0.003 |
Major vascular complications femoral access only by closure type | |||
Percutaneous closure device | 22 (4.0) | 39 (6.7) | 0.046 |
Surgical cutdown technique | 8 (9.3) | 9 (15.0) | 0.291 |
Bleeding | |||
Life‐threatening bleeding | 22 (2.9) | 19 (2.5) | 0.659 |
Major bleeding | 37 (4.8) | 44 (5.7) | 0.421 |
Life‐threatening and major | 59 (7.7) | 63 (8.2) | 0.706 |
Minor bleeding | 66 (8.6) | 55 (7.3) | 0.353 |
AKI | |||
Stage I | 85 (13.7) | 101 (14.8) | 0.548 |
Stage II and III | 24 (3.9) | 25 (3.7) | 0.859 |
Any stage | 109 (17.5) | 126 (18.5) | 0.646 |
Coronary occlusion | 5 (0.7) | 4 (0.5) | 0.738* |
Periprocedural Stroke | 11 (1.4) | 12 (1.6) | 0.831 |
Hospital‐acquired pneumonia | 11 (1.57) | 10 (1.33) | 0.690 |
New permanent pacemaker implantation | 91 (13) | 108 (15.6) | 0.158 |
Length of hospital stay, d | 6 [5–9] | 5 [3–8] | <0.001 |
Post‐TAVR echocardiogram parameters within 30‐d after TAVR | |||
Moderate‐severe post‐TAVR AR | 38 (5.0) | 18 (2.5) | 0.009 |
Postprocedural mean aortic valve gradient (mm Hg) | 8 [6–11] | 10 [7–14] | <0.001 |
Severe patient‐prosthesis mismatch | 7 (1.1) | 23 (3.5) | 0.004 |
Device success | 678 (88.1) | 650 (84.4) | 0.038 |
Echocardiogram parameters at 1‐y after TAVR | |||
1 y mean aortic valve gradient (mm Hg) | 8 [6–11] | 10 [7–14] | <0.001 |
Values are expressed as n (%) or median [IQR]. AKI indicates acute kidney injury; AR, aortic regurgitation; BMI, body mass index; and TAVR, transcatheter aortic valve replacement.
Fisher’s exact test used.