Table 1.
Baseline Characteristics of the Matched Patients
| Characteristic | Aortic Valve Morphological Feature | OR (95% CI) | P Value | |
|---|---|---|---|---|
| BAV | TAV | |||
| (n=274) | (n=274) | |||
| Men | 182 (66.4) | 182 (66.4) | 1.00 (0.79–1.27) | >.99 |
| Age at surgery, y | 67 (61–71) | 67 (61–71) | 1.00 (0.98–1.02) | >.99 |
| Body mass index, kg/m2 | 26.2 (24.1–28.9) | 27.5 (25.0–30.9) | 1.01 (1.04–1.13) | <0.001 |
| Smoking status | 270/274* | 264/274* | ||
| Never | 120 (43.8) | 125 (45.6) | 1.08 (0.77–1.51) | 0.731 |
| Former | 95 (34.7) | 97 (35.4) | 1.03 (0.73–1.46) | 0.929 |
| Currently | 55 (20.1) | 42 (15.3) | 0.72 (0.46–1.12) | 0.179 |
| Family history of CAD | 32 (11.68) | 39 (14.23) | 1.25 (0.76–2.07) | 0.443 |
| Diabetes mellitus | 40 (14.6) | 94 (34.3) | 3.06 (2.01–4.64) | <0.001 |
| Insulin dependent | 10 (3.6) | 34 (12.4) | 1.70 (0.74–3.90) | 0.233 |
| Hypertension | 142 (51.8) | 187 (68.2) | 2.00 (1.41–2.83) | <0.001 |
| Hypercholesterolemia | 77 (28.1) | 132 (48.2) | 2.38 (1.67–3.39) | <0.001 |
| Total cholesterol, mmol/L | 4.95±1.18 | 4.8 (4.00–5.30) | 0.91 (0.74–1.12) | 0.383 |
| HDL cholesterol, mmol/L | 1.34 (1.1–1.71) | 1.3 (1.07–1.52) | 1.01 (0.73–1.40) | 0.939 |
| LDL cholesterol, mmol/L | 2.82±0.93 | 2.85±1.21 | 1.00 (0.76–1.38) | 0.871 |
| Preoperative creatinine, mmol/L | 82 (72–92.5) | 81 (69–99) | 1.01 (1.001–1.013) | 0.007 |
| Previous CAD | ||||
| Previous MI | 12 (4.4) | 58 (21.2) | 5.86 (3.07–11.2) | <0.001 |
| Previous (i)AP | 12 (4.4) | 21 (7.7) | 1.81 (0.87–3.76) | 0.150 |
| Previous coronary revascularization | ||||
| Previous PCI | 12 (4.4) | 55 (20.1) | 5.48 (2.86–10.50) | <0.001 |
| Previous CABG | 2 (0.7) | 14 (5.1) | 7.32 (1.65–32.54) | 0.004 |
| Previous cardiac surgery | ||||
| CoA correction | 6 (2.2) | 0 | 0.978 (0.96–0.996) | 0.030 |
| AVP | 1 (0.5) | 1 (0.4) | 1.00 (0.62–16.07) | >.99 |
| Aorta surgery | 2 (0.7) | 0 | 0.99 (0.98–1.003) | 0.499 |
Data are presented as number (percentage), mean±SD, or median (interquartile range). (i)AP indicates (instable) angina pectoris; AVP, aortic valve plasty; BAV, bicuspid aortic valve; CABG, coronary artery bypass grafting; CAD, coronary artery disease; CoA, coarctation of the aorta; HDL, high‐density lipoprotein; LDL, low‐density lipoprotein; MI, myocardial infarction; OR, odds ratio; PCI, percutaneous coronary intervention; and TAV, tricuspid aortic valve.
*
Denominator represents number of patients for whom this information was known.