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. 2021 Jun 8;10(12):e021965. doi: 10.1161/JAHA.121.021965

Figure 3. Modified ARC HBR criteria and BARC 3 or 5 bleedings at 1 year.

Figure 3

Modified ARC HBR criteria (age, creatinine clearance, and hemoglobin analyzed as continuous variables) to predict BARC 3 or 5 bleedings at 1 year in males (M) and females (F): adjusted (Adj) bleeding incidence for minor and major (*) ARC‐HBR criteria (A) and score discrimination using Harrell's c‐index (B). Bold risk factors: cumulative incidence calculated for the mean of that risk factor. The dotted line indicates a 4% incidence of bleeding, expected in presence of a major ARC HBR criterion (definition in Table S1). ARC indicates Academic Research Consortium; BARC, Bleeding Academic Research Consortium; eGFR, glomerular filtration rate according to Modification of Diet in Renal Disease formula; HBR, high bleeding risk; int, interaction; and PCI, percutaneous coronary intervention. † P value for female vs male sex after adjustment for all other modified ARC‐HBR criteria.