Table 2.

Antibiotic resistance profiles of methicillin-resistant and multidrug-resistant oral coagulase-negative staphylococci (CoNS)

CoNS species	MR/MDR	Antimicrobial resistance profile (No. of antibiotics)	Methicillin resistance genes	SCCmec	MLS phenotype resistance
S. epidermidis	MR/MDR	FOX-ERY- CLI-GEN-TET-FAD-SXT (7)	mecA (+),mecC (-)	SCCmec IV	cMLSB
S. haemolyticus	MR/MDR	FOX-ERY-GEN-TET-SXT-FAD-CIP (7)	mecA (+),mec (-)	SCCmec V	MSB
S. haemolyticus	MR/MDR	FOX-ERY-CLI-GEN-SXT-CIP (6)	mecA (+),mecC (-)	SCCmec V	iMLSB
S. haemolyticus	MR/MDR	FOX-ERY-GEN-TET-SXT-CIP (6)	mecA (+),mecC (-)	SCCmec V	MSB
S. haemolyticus	MR/MDR	FOX-ERY-GEN-TET (4)	mecA (+),mecC (-)	SCCmec V	MSB
S. haemolyticus	MR	FOX	mecA (+),mecC (-)	SCCmec V	EryS
S. haemolyticus	MDR	ERY-CLI-GEN-TET	-	-	cMLSB
S. haemolyticus	MDR	PEN-ERY-CLI-GEN	-	-	cMLSB
S. haemolyticus	MDR	ERY-GEN-TET-SXT	-	-	MSB
S. saprophyticus	MR/MDR	FOX-ERY-GEN-TET-FAD-CHL (6)	mecA (+), mecC (-)	NT	MSB
S. saprophyticus	MDR	PEN-ERY-TET-FAD-CHL	-	-	MSB
S. saprophyticus	MDR	PEN-ERY-TET-FAD-SXT	-	-	MSB
S. saprophyticus	MR	FOX-FAD	mecA (+), mecC (-)	NT	EryS
S. warneri	MR/MDR	FOX-GEN-TET	mecA (+), mecC (-)	SCCmec IV	EryS
S. warneri	MR/MDR	FOX-ERY-GEN	mecA (+), mecC (-)	SCCmec IV	MSB
S. warneri	MR	FOX-GEN	mecA (+), mecC (-)	NT	EryS
S. hominis	MR/MDR	FOX-ERY-CLI-TET-FAD-SXT (5)	mecA (+), mecC (-)	SCCmec IV	cMLSB
S. hominis	MR/MDR	FOX-ERY-SXT	mecA (+), mecC (-)	SCCmec IV	iMLSB
S. succinus	MR/MDR	FOX-GEN-TET	mecA (+), mecC (-)	NT	EryS

FOX – cefoxitin, CIP – ciprofloxacin, CLI – clindamycin, ERY – erythromycin, FAD – fusidic acid, GEN – gentamicin, SXT – sulfamethoxazole/trimethoprim, TET – tetracycline, CoNS – coagulase-negative staphylococci, MR – methicillin-resistant, MDR – multidrug resistant, SCCmec – staphylococcal cassette chromosome mec, MLS – macrolide-lincosamide-streptogramin, NT- non-typeable