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. 2019 Oct 11;44(5):789–793. doi: 10.1080/10790268.2019.1658283

Table 1. Cases of syphilitic myelitis reported previously and current case.

Case Age Sex Time to the initial infection of syphilis Time between onset to nadir MRI findings of spinal cord Treatment Recovery
Tashiro-198711 31 M 7 months 10 days Thoracic spinal cord, enhancement at the level of T3/4 Penicillin G with prednisolone Yes(about 1 month later)
Strom-199114 28 M NA 6 months Hyperintense on T2 from T6-8 Penicillin G with dexamethasone Partial relief
Nabatame-199215 46 M NA NA Thoracic spinal cord, Candle guttering appearance and abnormal enhancement in the central part of spinal cord Antibiotic treatment Yes
Bulundwe-200016 53 M NA 11 months Hyperintense with swelling on T2 from T3-6 Penicillin G Yes
Tsui-200212 52 F 2 years 5 days Whole spinal cord, Candle guttering appearance and abnormal enhancement in the central part of spinal cord Penicillin G with dexamethasone wheelchair
Kikuchi-200317 36 M NA 3 months Abnormal signals involving the whole spinal cord, Candle guttering appearance and flip-flop sign Penicillin G Yes(about 1 month later)
Matijošaitis 200618 38 M About 1.5 years 4 months Hyperintense on T2 from T6-8, ring-like enhancement Penicillin G with prednisone Partial relief
Chilver-200919 46 M NA 7 days Abnormal signals below T6, Candle guttering appearance and abnormal enhancement in the central part of spinal cord Penicillin G with methylprednisolone Yes(about 3 months later)
Dongmei He-201420 63 M NA 12 days T6-11, Candle guttering appearance and abnormal enhancement in the central part of spinal cord Ceftriaxone with methylprednisolone Yes(about 3 months later)
Siu-201721 41 M NA NA spinal cord edema at C3 through T1 levels, with focal spinal cord enhancement at C6 Penicillin G Yes(about1 week later)
Sun-201822 50 F NA 2.5 months Hyperintense with swelling on T2 from T1 to T10, Candle guttering appearance with flip-flop sign Penicillin G, Ceftriaxone with methylprednisolone Yes(about1 week later)
This case 29 F 2 years 6 months Whole thoracic spinal cord, Candle guttering appearance with flip-flop sign Penicillin G with dexamethasone Yes(about 6 months later)