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. 2021 Sep 24;14:4901–4914. doi: 10.2147/OTT.S286326

Figure 6.

Figure 6

miR-425-5p inhibits AML progression by targeting WTAP. (A) The expression of WTAP was measured by qPCR in the KG-1A cells transfected with pcDNA3.1 or pcDNA3.1-WTAP overexpression vector. (BE) The KG-1A cells were treated with control mimic, miR-425-5p mimic, or co-treated with miR-425-5p mimic and pcDNA3.1-WTAP overexpression vector. (B) The cell proliferation was tested by colony formation assay in the cells. (C) The cell apoptosis was measured by flow cytometry analysis in the cells. (D) The cell proliferation was analyzed by Edu assays in the cells. (E) The invasion and migration were assessed by transwell assays in the cells. Data are presented as mean ± SD. Statistic significant differences were indicated: *P < 0.05, **P < 0.01, ***P < 0.001.