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. 2021 Sep 24;14:3949–3960. doi: 10.2147/IDR.S330115

Table 4.

Comparison of mCIM, sCIM and CIM-s in the Detection of Carbapenemase

PCR (n) Zone (mm) Positive (n, %) Indeterminate (n, %)
mCIM sCIM CIM-s* mCIM sCIM CIM-s* mCIM sCIM CIM-s*
Positive (79) 6–10 6–25 6–20 79(100) 73(92.4) 77(97.5) 0(0) 6(7.6) 2(2.5)
 CphA (68) 6–10 6–25 6–20 68(100) 62(91.2) 66(97.1) 0(0) 6(8.2) 2(2.9)
 KPC-2 (6) 6 6 6 6(100) 6(100) 6(100) 0(0) 0(0) 0(0)
 NDM-1 (2) 6 6–10 6 2(100) 2(100) 2(100) 0(0) 0(0) 0(0)
 KPC-2+CphA (3) 6 6 6 3(100) 3(100) 3(100) 0(0) 0(0) 0(0)
Negative (52) 21–23 26–30 21–23 0(0) 0(0) 0(0) 0(0) 0(0) 0(0)

Notes: *The results were determined after incubation at 35°C in ambient air for 4h.

Abbreviations: mCIM, modified carbapenem inactivation method; sCIM, simplified carbapenem inactivation method; CIM-s, carbapenem inactivation method using supernatant.