Table 4.
Comparison of mCIM, sCIM and CIM-s in the Detection of Carbapenemase
| PCR (n) | Zone (mm) | Positive (n, %) | Indeterminate (n, %) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| mCIM | sCIM | CIM-s* | mCIM | sCIM | CIM-s* | mCIM | sCIM | CIM-s* | |
| Positive (79) | 6–10 | 6–25 | 6–20 | 79(100) | 73(92.4) | 77(97.5) | 0(0) | 6(7.6) | 2(2.5) |
| CphA (68) | 6–10 | 6–25 | 6–20 | 68(100) | 62(91.2) | 66(97.1) | 0(0) | 6(8.2) | 2(2.9) |
| KPC-2 (6) | 6 | 6 | 6 | 6(100) | 6(100) | 6(100) | 0(0) | 0(0) | 0(0) |
| NDM-1 (2) | 6 | 6–10 | 6 | 2(100) | 2(100) | 2(100) | 0(0) | 0(0) | 0(0) |
| KPC-2+CphA (3) | 6 | 6 | 6 | 3(100) | 3(100) | 3(100) | 0(0) | 0(0) | 0(0) |
| Negative (52) | 21–23 | 26–30 | 21–23 | 0(0) | 0(0) | 0(0) | 0(0) | 0(0) | 0(0) |
Notes: *The results were determined after incubation at 35°C in ambient air for 4h.
Abbreviations: mCIM, modified carbapenem inactivation method; sCIM, simplified carbapenem inactivation method; CIM-s, carbapenem inactivation method using supernatant.