Table 5.
Sensitivity and Specificity of Phenotypic Tests and IMP (95% CI)
| Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Accuracy (%) | |
|---|---|---|---|---|---|
| mCIM | 100 (95.4–100) | 100 (93.2–100) | 100 (95.4–100) | 100 (93.2–100) | 100 (97.2–100) |
| sCIM | 92.4 (84.2–97.2) | 100 (93.2–100) | 100 (95.1–100) | 89.7 (78.8–96.1) | 95.4 (90.3–98.3) |
| CIM-s* | 97.5 (91.2–99.7) | 100 (93.2–100) | 100 (95.3–100) | 96.3 (87.3–99.6) | 98.5 (94.6–99.8) |
| IMP** | 91.1 (82.6–96.4) | 100 (93.2–100) | 100 (95.0–100) | 88.1 (77.1–95.1) | 94.7 (89.3–97.8) |
Notes: *The results were determined after incubation at 35°C in ambient air for 4 h. **Resistance to imipenem tested by Vitek-2 compact system.
Abbreviations: mCIM, modified carbapenem inactivation method; sCIM, simplified carbapenem inactivation method; CIM-s, carbapenem inactivation method using supernatant; IMP, imipenem; CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value.