Table 3.

Top 20 targets of the protein-protein interaction network.

No.	Targets	Degree	Betweenness centrality	Closeness centrality
1	PIK3CA	45	0.056863	0.420118
2	MAPK1	44	0.146963	0.441909
3	PIK3R1	43	0.045671	0.418468
4	SRC	41	0.048756	0.416016
5	APP	38	0.124074	0.394444
6	HRAS	35	0.020650	0.375661
7	STAT3	34	0.097739	0.408829
8	HSP90AA1	31	0.087902	0.407266
9	NRAS	30	0.017837	0.365352
10	FYN	29	0.009133	0.381720
11	AKT1	27	0.048552	0.397388
12	EGFR	27	0.044610	0.404175
13	JAK2	27	0.011099	0.370435
14	MAPK8	27	0.031883	0.401887
15	LCK	26	0.005706	0.376991
16	PRKCD	26	0.040957	0.387273
17	PTPN11	24	0.005269	0.371080
18	NMUR2	24	0.017057	0.345779
19	JAK1	23	0.004552	0.372378
20	RELA	23	0.036432	0.401130