Table 2.
Groups | Body weight (g) | Rectal temperature (°C) | ||||
---|---|---|---|---|---|---|
D0 | D4 | % change | D0 | D4 | % change | |
DW | 26.92 ± 0.83 | 22.50 ± 1.13 | −16.58 | 37.25 ± 0.21 | 34.33 ± 0.42 | −7.84 |
CE (mg/kg) | ||||||
100 | 27.67 ± 1.21 | 24.83 ± 1.15 | −10.27a1b3 | 36.75 ± 0.21 | 34.25 ± 0.21 | −6.80b3 |
200 | 27.58 ± 1.46 | 26.08 ± 1.36 | −5.42a3b3 | 36.67 ± 0.21 | 35.08 ± 0.35 | −4.32a2b3 |
400 | 26.92 ± 0.79 | 27.00 ± 0.62 | 0.41a3b2 | 37.00 ± 0.29 | 35.67 ± 0.31 | −4.96a1b3 |
CQ25 mg/kg | 27.33 ± 0.63 | 29.67 ± 0.76 | 8.54a3 | 36.92 ± 0.30 | 37.25 ± 0.17 | 0.92a3 |
Data are expressed as mean ± SEM; n = 6. DW = distilled water, CE = crude extract, CQ = chloroquine, D0 = day 0, D4 = day 4, a = compared to negative control, b = compared to a standard drug, 1 = p < 0.05, 2 = p < 0.01, and 3 = p < 0.001.