Figure 4.

Representative examples of new lesions on the W4 PET-CT scan with 3D renderings

(A) Large right upper lobe cavity (red) with surrounding dense consolidation (green) and smaller left segments 1–3 cavities (pink) with surrounding consolidation (blue). All cavities shrank by W4. There was a new left side lingular infiltrate (blue arrows, green-brown lesion on 3D rendering) at W4 that was not present at W0. (B) At baseline, there was a large posterior left upper lobe S1–2 cavity (red) with small anterior S3 cavity (red) at baseline and associated consolidation (green) primarily in left S1–2 down to the lingula S4–5. There was also an extensive left lower lobe consolidation (yellow) as well. At W4, left S1–2 segment cavity had decreased in size but with markedly increased PET uptake around it. Left lower lobe consolidation, however, had improved. There was a new left S3 segment consolidation (blue arrows, pink lesion on 3D rendering) that was not present at baseline. (C) At baseline, there were cavities (red) with associated consolidations in the right upper lobe, apex of the left lower lobe, and in the left base. At W4, all of these had improved but there was a new left lingular lesion (blue arrows, blue lesion on 3D rendering) that was not present at baseline. (D) At baseline, disease was confined to the right upper lobe with a S1 cavity, surrounding consolidation, and spread of disease to the S3 segment. At W4, there were two new foci of nodular disease (blue arrows, purple lesion on the 3D rendering) in the right lower lobe S8 segment. 3D=three-dimensional. W=week.