Table 2.

Administration regimen of the study drug and sedation

		Loading dose	Maintenance dose	Allowed top-up dose during maintenance administration
Study drug used for sedation	Ciprofol group	0.1 mg/kg, 4 min ± 30 s, intravenous infusion	Start maintenance at 0.3 mg/kg/h, dose can be up- or downregulated at 0.05 ~ 0.1 mg/kg/h; the range of the maintenance dose: 0.06 ~ 0.8 μg/kg/min	0.05 mg/kg each time, each top-up should have at least 2-min time intervals
	Propofol group	0.5 mg/kg, 4 min ± 30 s, intravenous infusion	Start maintenance at 1.5 mg/kg/h, dose can be up- or downregulated at 0.25 ~ 0.5 mg/kg/h, the range of maintenance dose: 0.3 ~ 4 μg/kg/min	0.25 mg/kg each time, each top-up should have at least a 2-min time interval
Remifentanil used for analgesia		NA	Range of the maintenance dose: 0.02 ~ 0.15 μg/kg/min	NA