Table 2.
The 2017 prevalence of metabolic acidosis defined by ICD codes and agreement with metabolic acidosis defined by laboratory values
| Prevalence of metabolic acidosis (bicarbonate labs) (%)1 | Prevalence of metabolic acidosis (ICD codes) (%)2 | Sensitivity (%)3 | Specificity (%)4 | Concordance (%)5 | |
|---|---|---|---|---|---|
| CKD and hyperkalemia > 5.0 mEq/l | |||||
| Bicarbonate < 22 mEq/l | 24.50 | 8.17 | 21.74 | 96.24 | 77.99 |
| Bicarbonate < 18 mEq/l | 5.50 | 8.17 | 40.73 | 93.73 | 90.81 |
| CKD and hyperkalemia > 5.5 mEq/l | |||||
| Bicarbonate < 22 mEq/l | 33.05 | 13.31 | 25.57 | 92.75 | 70.54 |
| Bicarbonate < 18 mEq/l | 10.13 | 13.31 | 38.84 | 89.57 | 84.44 |
CKD chronic kidney disease, ICD International Classification of Disease
1All analyses represent the prevalence in 2017
2ICD codes to identify metabolic acidosis included ICD-9-CM 276.2 and ICD-10-CM E87.2
3Sensitivity is the probability of having an ICD code for metabolic acidosis among patients with metabolic acidosis defined by the serum bicarbonate laboratory value
4Specificity is the probability of not having an ICD code for metabolic acidosis among patients without metabolic acidosis defined by the serum bicarbonate laboratory value
5Concordance is the probability of having an ICD code for metabolic acidosis and a serum bicarbonate laboratory value in agreement