Table 2.

Reduced Gray Matter Volume Associated with Childhood Blood Concentrations at Age 78 Months

Anatomical Region	Cluster Size (Voxels)	Peak Voxel MNI Coordinates (X,Y,Z)	Peak Voxel TFCE	Voxel P-Value
Cingulate Medial Frontal Gyrus Superior Frontal Gyrus	1291	0 35 32	8814.85	0.043
Cingulate Medial Frontal Gyrus Paracentral Lobule Supplementary Motor Area	844	−2 −21 48	8687.25	0.046
Medial Frontal Gyrus Supplementary Motor Area	444	0 −6 63	8720.01	0.046

Model adjusted for age at time of imaging, birth weight and total intracranial volume. Voxels and clusters corrected for multiple comparisons (FWE) at P ≤ 0.05 using TFCE. FWE = Familywise Error Rate; MNI = Montreal Neurological Institute; TFCE = Threshold Free Cluster Enhancement