Table 2.
Mixed models analysis results – estimates of fixed effects.
| Alcohol Craving | Stop Signal Reaction Time (SSRT) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| Fixed Effects | Est | SE | t | p |
95% CI
|
Est | SE | t | p |
95% CI
|
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| LL | UL | LL | UL | |||||||||
| Intercept | 2.68 | 0.41 | 6.60 | 0.000 | 1.87 | 3.50 | 212.33 | 36.39 | 5.84 | 0.000 | 139.21 | 285.45 |
| Baseline Percent Days Drinking | −0.53 | 0.33 | −1.59 | 0.117 | −1.19 | 0.14 | 5.20 | 30.51 | 0.17 | 0.865 | −56.12 | 66.51 |
| Depression Severity | 0.02 | 0.02 | 0.83 | 0.410 | −0.03 | 0.06 | −0.38 | 2.04 | −0.19 | 0.854 | −4.47 | 3.72 |
| PTSD Severity | 0.02 | 0.02 | 1.07 | 0.292 | −0.02 | 0.05 | 1.37 | 1.47 | 0.93 | 0.356 | −1.58 | 4.31 |
| AUD Severity | −0.01 | 0.02 | −0.31 | 0.756 | −0.04 | 0.03 | −3.00 | 1.61 | −1.86 | 0.068 | −6.23 | 0.23 |
| Time: Post-Stressor/Post-CR/ sitting quietly (SQ) | 0.23 | 0.20 | 1.15 | 0.256 | −0.17 | 0.63 | 8.08 | 29.60 | 0.27 | 0.786 | −51.42 | 67.59 |
| Condition | −0.64 | 0.63 | −1.02 | 0.311 | −1.91 | 0.62 | −69.13 | 55.98 | −1.24 | 0.223 | −181.64 | 43.38 |
| Condition*Time | 0.07 | 0.33 | 0.22 | 0.826 | −0.59 | 0.74 | 4.63 | 48.78 | 0.10 | 0.925 | −93.46 | 102.72 |
| AUDIT interactions: | ||||||||||||
| Post-Stressor*Control | 0.04 | 0.02 | 1.82 | 0.074 | −0.00 | 0.09 | 5.47 | 2.48 | 2.20 | 0.031 | 0.51 | 10.42 |
| Post-CR/SQ* Control | 0.02 | 0.02 | 1.03 | 0.308 | −0.02 | 0.07 | 6.45 | 2.16 | 3.00 | 0.004 | 2.12 | 10.77 |
| Post-Stressor*CR | −0.02 | 0.01 | −1.96 | 0.055 | −0.04 | 0.00 | 1.96 | 1.41 | 1.40 | 0.168 | −0.86 | 4.79 |
| Post-CR/SQ*CR (ref) | – | – | – | – | – | – | – | – | – | – | – | – |
| BDI interactions: | ||||||||||||
| Post-Stressor*Control | 0.03 | 0.03 | 0.90 | 0.374 | −0.03 | 0.09 | −0.64 | 3.06 | −0.21 | 0.836 | −6.75 | 5.48 |
| Post-CR/SQ* Control | 0.02 | 0.03 | 0.68 | 0.501 | −0.04 | 0.08 | −0.05 | 2.68 | −0.02 | 0.986 | −5.42 | 5.33 |
| Post-Stressor*CR | −0.02 | 0.01 | −1.35 | 0.184 | −0.04 | 0.01 | 2.08 | 1.77 | 1.18 | 0.245 | −1.47 | 5.64 |
| Post-CR/SQ*CR (ref) | – | – | – | – | – | – | – | – | – | – | – | – |
| PCL interactions: | ||||||||||||
| Post-Stressor*Control | −0.02 | 0.02 | −1.02 | 0.311 | −0.06 | 0.02 | 0.25 | 2.18 | 0.11 | 0.91 | −4.11 | 4.61 |
| Post-CR/SQ* Control | −0.01 | 0.02 | −0.53 | 0.599 | −0.05 | 0.03 | −1.10 | 1.91 | −0.58 | 0.568 | −4.94 | 2.74 |
| Post-Stressor*CR | 0.02 | 0.01 | 1.83 | 0.074 | −0.00 | 0.03 | −1.25 | 1.28 | −0.98 | 0.331 | −3.82 | 1.31 |
| Post-CR/SQ*CR (ref) | – | – | – | – | – | – | – | – | – | – | – | – |
Note:Bolded values represent simple effects interpreted due to significant interactive fixed effects in the mixed model analysis.
Depression severity assessed with BDI-II; PTSD severity with PCL-5; AUD severity with AUDIT (see Methods for details); Cond = Condition [Control vs. Cognitive Reappraisal/CR (CR Reference)].
Est = Beta Estimate, SE = Parameter Standard Error, CI = Confidence Interval, LL = Lower Limit, UL = Upper Limit.