TABLE 3.
Magnitude of the Association of Variables With Nonadherence to Oral 6MP
| Adherence Model |
|||
|---|---|---|---|
| Variablea | OR | 95% CI | P |
| Age at study (per year increase) | 1.09 | 1.02-1.17 | .01 |
| Hispanicb | 3.31 | 1.48-7.44 | .004 |
| Asianb | 2.57 | 0.93-7.15 | .07 |
| African Americanb | 4.90 | 1.85-12.99 | .001 |
| Absolute neutrophil count | 1.39 | 1.11-1.74 | .004 |
| 6MP dose intensityc | 11.21 | 2.75-45.74 | .0008 |
| Single parent/single childd | 0.67 | 0.15-2.99 | .6 |
| Single parent/multiple childrend | 3.66 | 1.35-9.92 | .01 |
| 6MP ingestion patterne | 0.63 | 0.33-1.20 | .2 |
Abbreviations: 6MP, mercaptopurine; CI, confidence interval; OR, odds ratio.
Includes variables retained in the risk prediction model.
Compared with non-Hispanic Whites.
OR per 1-unit increase in the absolute neutrophil count or 6MP dose intensity.
Compared with a nuclear family.
Ingested at the same time of day versus varying time of day.