Table 2.
Significant tissues relevant to vBMDs
| Trait | Name | Coefficient | Coefficient P value |
|---|---|---|---|
| L2 integral vBMD | Esophagus Mucosa | 1.73E-11 | 0.010 |
| Skin Not Sun Exposed (Suprapubic) | 1.38E-11 | 0.015 | |
| Heart Left Ventricle | 1.35E-11 | 0.020 | |
| Adrenal Gland | 1.42E-11 | 0.025 | |
| Heart Atrial Appendage | 9.88E-12 | 0.038 | |
| Brain - Spinal cord (cervical c-1) | 9.94E-12 | 0.040 | |
| L2 trabecular vBMD | Esophagus Mucosa | 1.84E-11 | 0.003 |
| Adrenal Gland | 1.39E-11 | 0.017 | |
| Heart Left Ventricle | 1.21E-11 | 0.021 | |
| Skin Not Sun Exposed (Suprapubic) | 1.21E-11 | 0.022 | |
| Transverse Colon | 1.19E-11 | 0.045 | |
| L3 integral vBMD | Heart Left Ventricle | 1.66E-12 | 0.011 |
| Adrenal Gland | 1.67E-12 | 0.014 | |
| Esophagus Mucosa | 1.48E-12 | 0.020 | |
| Transverse Colon | 2.08E-12 | 0.021 | |
| L2 trabecular vBMD | Heart Left Ventricle | 1.87E-12 | 0.004 |
| Adrenal Gland | 2.01E-12 | 0.009 | |
| Esophagus Mucosa | 1.75E-12 | 0.013 | |
| Transverse Colon | 1.97E-12 | 0.026 | |
| Heart Atrial Appendage | 1.14E-12 | 0.040 | |
| Skin Not Sun Exposed (Suprapubic) | 1.28E-12 | 0.049 | |
| L4 integral vBMD | Transverse Colon | 2.88E-12 | 0.017 |
| Adrenal Gland | 2.05E-12 | 0.019 | |
| Heart Left Ventricle | 1.81E-12 | 0.027 | |
| Esophagus Mucosa | 1.85E-12 | 0.034 | |
| Skeletal Muscle | 1.69E-12 | 0.034 | |
| L4 trabecular vBMD | Transverse Colon | 3.68E-12 | 0.007 |
| Heart Left Ventricle | 2.50E-12 | 0.011 | |
| Esophagus Mucosa | 2.57E-12 | 0.015 | |
| Adrenal Gland | 2.21E-12 | 0.024 | |
| Skeletal Muscle | 2.10E-12 | 0.027 | |
| Skin Not Sun Exposed (Suprapubic) | 2.30E-12 | 0.031 | |
| Esophagus Muscularis | 1.88E-12 | 0.041 | |
| FN cortical vBMD | Heart Left Ventricle | 8.20E-12 | <0.001 |
| Heart Atrial Appendage | 4.22E-12 | 0.006 | |
| Stomach | 4.26E-12 | 0.024 | |
| Artery Tibial | 3.55E-12 | 0.024 | |
| Lung | 3.11E-12 | 0.032 | |
| FN trabecular vBMD | Heart Left Ventricle | 3.95E-12 | <0.001 |
| Heart Atrial Appendage | 2.01E-12 | 0.007 | |
| Stomach | 2.08E-12 | 0.023 | |
| Artery Tibial | 1.74E-12 | 0.024 | |
| Lung | 1.53E-12 | 0.031 | |
| FN integral vBMD | Heart Left Ventricle | 6.93E-12 | <0.001 |
| Heart Atrial Appendage | 3.57E-12 | 0.006 | |
| Stomach | 3.60E-12 | 0.023 | |
| Artery Tibial | 2.99E-12 | 0.024 | |
| Lung | 2.63E-12 | 0.031 |
Notes: Bold tissues are associated with multiple vBMD traits at lumbar spine or femoral neck, respectively.