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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Biochem Pharmacol. 2021 Jul 16;192:114688. doi: 10.1016/j.bcp.2021.114688

Fig. 4.

Fig. 4.

Results of alkylation studies of STAT3 by iodoacetamide, NEM and TTI-101. Schematic depicting chemistry of possible alkylation of STAT3 by iodoacetamide the results of LC-MS chromatograms of STAT3 peptides demonstrating alkylated peptides, as predicted from the chemistry. Schematic depicting chemistry of possible alkylation of STAT3 by NEM the results of LC-MS chromatograms of STAT3 peptides demonstrating alkylated peptides, as predicted from the chemistry. Schematic depicting the chemistry of possible alkylation of STAT3 by TTI-101. The LC-MS chromatograms of STAT3 peptides, that, shows no MRM signal for predicted peptide adducts, indicating that no peptides were alkylated.