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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: Neuropharmacology. 2021 Jul 13;197:108713. doi: 10.1016/j.neuropharm.2021.108713

Fig. 3. Changes in NAc oxygen levels induced by iv heroin (0.2 mg/kg) after intragastric administration of alcohol (2.0 g/kg) or water in awake, freely moving rats analyzed at slow time-resolution.

Fig. 3.

A - changes induced by administration of alcohol (2.0 g/kg) and water; B, C and D – changes induced by heroin delivered at 20, 80, and 140 min after intragastric administration of alcohol or water. Filled symbols mark values significantly different from pre-event baseline (p<0.05). Vertical dotted lines (0, min) show the onset of ig alcohol delivery (A) and iv heroin injection (B-D). See the text and Supplemental Materials for quantitative results of statistical evaluations.