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Canonical Pathways affected in both male and female DKO bones
| Pathway | P value | Z score |
|---|---|---|
| Leukocyte Extravasation Signaling | 3.3E-11 | −3.7 |
| EIF2 signaling | 2.27E-10 | 3.4 |
| Production of NO and ROS by macrophages | 1.17E-06 | −3.0 |
| Pentose Phosphate | 1.29E-06 | −2.8 |
| Integrin | 7.25E-04 | −2.8 |
| GP6 signaling | 1.27E-05 | −2.8 |
| p70S6K signaling | 6.34E-03 | −2.2 |
| Sirtuin signaling | 3.27E-04 | 2.3 |
