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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Br J Sports Med. 2021 Mar 29;56(2):101–106. doi: 10.1136/bjsports-2020-103640

Table 3.

Population Attributable Risks Associated with Physical Inactivity in Different Geographical Regions

Outcome Central Asia, Middle East, & North Africa Central & Eastern Europe East & Southeast Asia High-Income Asia Pacific High-Income Western Countries Latin America & Caribbean Oceania South Sub-Saharan Africa
Prevalence (95% CI)*,ǂ 32.8 (31.0 to 32.2) 23.4 (20.9 to 28.0) 17.3 (15.8 to 22.1) 35.7 (34.4 to 37.0) 36.8 (34.6 to 38.4) 39.1 (37.8 to 40.6) 16.3 (14.3 to 20.7) 33.0 (23.0 to 51.7) 21.4(19.1 to 23.3)
PARsemi (95% CI)
All-Cause Mortality 8.4 (6.5 to 10.4) 6.2 (4.6 to 7.8) 4.6 (3.4 to 6.0) 9.1 (7.0 to 11.2) 9.3 (7.2 to 11.5) 9.9 (7.7 to 12.2) 4.4 (3.2 to 5.6) 8.5 (5.0 to 12.3) 5.7 (4.3 to 7.1)
CVD Mortality 9.0 (7.4 to 10.6) 6.6 (5.2 to 8.0) 4.9 (3.9 to 6.1) 9.7 (8.1 to 11.4) 9.9 (8.3 to 11.7) 10.5 (8.7 to 12.4) 4.7 (3.6 to 5.8) 9.0 (5.5 to 12.8) 6.0 (3.9 to 7.2)
Coronary Heart Disease 5.9 (4.2 to 7.6) 4.3 (3.0 to 5.7) 3.2 (2.2 to 4.3) 6.4 (4.6 to 8.2) 6.5 (4.7 to 8.4) 6.9 (5.0 to 8.9) 3.0 (2.1 to 4.1) 5.9 (3.3 to 9.0) 3.9 (2.8 to 5.2)
Stroke 5.9 (3.5 to 8.5) 4.3 (2.5 to 6.2) 3.2 (1.8 to 4.7) 6.4 (3.8 to 9.2) 6.5 (3.9 to 9.4) 6.9 (4.1 to 10.0) 3.0 (1.7 to 4.4) 5.9 (2.9 to 9.6) 3.9 (2.2 to 5.7)
Hypertension 1.9 (1.1 to 2.8) 1.4 (0.8 to 2.0) 1.0 (0.6 to 1.5) 2.1 (1.2 to 3.0) 2.2 (1.3 to 3.1) 2.3 (1.3 to 3.3) 1.0 (0.6 to 1.4) 1.9 (1.0 to 3.2) 1.3 (0.7 to 1.8)
Type 2 Diabetes 5.3 (3.8 to 6.9) 3.8 (2.7 to 5.1) 2.9 (2.0 to 3.9) 5.7 (4.0 to 7.5) 5.9 (4.2 to 7.7) 6.2 (4.5 to 8.1) 2.7 (1.8 to 3.7) 5.3 (3.0 to 8.0) 3.5 (2.5 to 4.6)
Bladder Cancer 2.6 (−1.4 to 7.1) 1.8 (−1.0 to 5.2) 1.4 (−0.8 to 3.8) 2.8 (−1.5 to 7.7) 2.9 (−1.7 to 7.9) 3.0 (−1.7 to 8.5) 1.3 (−0.7 to 3.6) 2.6 (−1.5 to 7.5) 1.7 (−0.9 to 4.7)
Breast Cancer* 3.5 (1.6 to 5.4) 2.2 (0.9 to 3.5) 1.5 (0.6 to 2.5) 3.3 (1.5 to 5.3) 3.7 (1.6 to 5.8) 3.8 (1.8 to 6.0) 1.8 (0.8 to 2.9) 3.7 (1.4 to 6.7) 2.2 (1.0 to 3.5)
Colon Cancer 3.5 (1.4 to 5.7) 2.5 (1.0 to 4.2) 1.9 (0.7 to 3.2) 3.8 (1.6 to 6.1) 3.9 (1.6 to 6.4) 4.1 (1.7 to 6.7) 1.8 (0.7 to 2.9) 3.5 (1.3 to 6.3) 2.3 (0.9 to 3.7)
Endometrial Cancer* 3.5 (−0.6 to 8.0) 2.2 (−0.3 to 5.1) 1.5 (−0.3 to 3.5) 3.3 (−0.5 to 7.6) 3.7 (−0.6 to 8.3) 3.8 (−0.6 to 8.7) 1.8 (−0.3 to 4.2) 3.7 (−0.6 to 9.3) 2.2 (−0.4 to 5.0)
Esophageal Cancer 8.4 (−3.0 to 24.4) 6.2 (−2.1 to 17.9) 4.6 (−1.7 to 13.7) 9.1 (−3.2 to 26.6) 9.3 (−3.3 to 27.7) 9.9 (−3.5 to 29.2) 4.4 (−1.6 to 12.9) 8.5 (−2.9 to 25.9) 5.7 (−2.0 to 16.6)
Gastric Cancer 8.1 (−0.3 to 19.0) 5.9 (−0.2 to 14.2) 4.5 (−0.2 to 10.6) 8.8 (−0.6 to 20.5) 9.0 (−0.4 to 21.6) 9.6 (−0.5 to 22.3) 4.2 (−0.2 to 10.1) 8.2 (−0.3 to 20.3) 5.5 (−0.2 to 12.8)
Renal Cancer 8.4 (2.8 to 14.9) 6.2 (2.1 to 11.1) 4.6 (1.6 to 8.3) 9.1 (3.0 to 16.3) 9.3 (3.1 to 16.8) 9.9 (3.4 to 17.4) 4.4 (1.4 to 7.9) 8.5 (2.5 to 16.2) 5.7 (1.8 to 10.2)
Dementia 9.5 (2.8 to 17.5) 7.0 (2.2 to 12.9) 5.3 (1.6 to 9.7) 10.3 (3.2 to 18.8) 10.5 (3.3 to 19.1) 11.1 (3.6 to 20.4) 5.0 (1.5 to 9.3) 9.6 (2.6 to 19.1) 6.4 (2.0 to 11.8)
Depression 8.4 (1.5 to 16.9) 6.2 (1.0 to 12.4) 4.6 (0.8 to 9.4) 9.1 (1.6 to 18.4) 9.3 (1.5 to 18.7) 9.9 (1.7 to 20.0) 4.4 (0.8 to 9.0) 8.5 (1.3 to 18.1) 5.7 (1.0 to 11.4)
*

The prevalence of insufficient physical activity among women (Central Asia, Middle East & North Africa: 39.9 %; 95% CI: 37.9 to 42.7; Central & Eastern Europe: 24.7%; 95% CI: 21.7 to 33.9; East & Southeast Asia: 16.9%; 95% CI: 14.9 to 25.7; High-Income Asia Pacific: 38.3%; 95% CI: 37.4 to 42.6; High-Income Western: 42.3%; 95% CI: 39.1 to 45.4; Latin America & Caribbean: 43.7%; 95% CI: 42.9 to 46.5; Oceania: 203.%; 95% CI: 18.8 to 28.7; South Asia: 43.0%; 95% CI: 29.6 to 74.9; Sub-Saharan Africa: 24.8%; 95% CI: 21.8 to 27.2) was applied to compute the PARsemi for breast cancer and endometrial cancer.

ǂ

Prevalence estimates were obtained from Guthold et al.4