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. 2021 Aug 28;12(10):2677–2690. doi: 10.1007/s13300-021-01139-2

Table 2.

Mean pancreatic enzyme levels at baseline and Week 26 in Chinese patients with T2DM receiving dulaglutide 1.5 mg, stratified by potential influencing factors

Subgroup n Pancreatic amylase, U/L Total amylase, U/L Lipase, U/L
BL W26 BL W26 BL W26
Age
 < 60 years 143 24.06 30.18 54.78 62.46 38.31 51.42
 ≥ 60 years 60 28.23 34.23 62.18 69.40 43.63 52.77
Sex
 Male 120 25.63 31.77 57.35 64.66 40.18 52.42
 Female 83 24.81 30.78 56.42 64.19 39.46 51.00
Duration of diabetes
 < 10 years 145 23.99 30.82 55.01 63.51 37.71 51.72
 ≥ 10 years 58 28.55 32.53 61.86 66.56 45.31 52.00
Baseline weight
 < 70 kg 89 24.74 31.22 58.42 65.85 39.67 52.20
 ≥ 70 kg 114 25.73 31.45 55.84 63.33 40.04 51.50
Body mass index
 < 25 kg/m2 88 24.93 31.17 57.11 65.60 39.57 49.74
 ≥ 25 kg/m2 115 25.57 31.48 56.86 63.61 40.12 53.33
Baseline HbA1c
 < 8.5% 123 26.21 32.83 58.02 66.63 40.27 54.86
 ≥ 8.5% 80 23.89 29.04 55.36 61.07 39.29 47.07
Baseline triglycerides
 < 2.3 mmol/L 149 26.38 31.40 57.54 64.18 41.01 51.04
 ≥ 2.3 mmol/L 54 22.31 31.19 55.41 65.25 36.78 53.98
Concomitant OAMs
 Metformin only 87 24.70 31.10 54.91 63.05 39.59 51.23
 SU only 30 25.10 30.71 56.47 63.92 39.83 49.29
 Metformin + SU 86 25.97 31.76 59.23 65.92 40.20 53.07

BL baseline, HbA1c glycated hemoglobin, OAM oral antihyperglycemic medication, SU sulfonylurea, W26 Week 26