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(A) Construction of the in vitro BBB model. bEnd3 cells were used to build the BBB model. (B) After four different treatments for 24 h, the survival state of U251 cells in each group was observed under a microscope. (C) The cell viability of U251 cells in each group was detected by the CCK-8 reagent. The cell viability of the FUS + GA/PLGA group was 55.83 ± 10.99% (***p < 0.001 versus the other group).
