TABLE 2.
Platelet activation biomarkers | Dabigatran (n = 33) | Rivaroxaban (n = 72) | p Value |
---|---|---|---|
ΔTAT | 13.52 ± 4.17 | 2.04 ± 1.88 | 0.001* |
ΔP-selectin | 14.40 ± 2.16 | 4.79 ± 1.42 | 0.031* |
ΔvWF | 63.82 ± 11.95 | 19.57 ± 6.27 | 0.007* |
ΔCD40L | 30.88 ± 13.83 | 18.02 ± 9.23 | 0.543 |
Intraindividual plasma platelet activation biomarkers variation followed by 3-month post-anticoagulation with dabigatran or rivaroxaban. Δ referred to variation of platelet activation biomarkers; TAT, thrombin–antithrombin complex; vWF, von Willebrand disease.