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. 2021 Sep 15;12:723905. doi: 10.3389/fphar.2021.723905

TABLE 2.

Comparison of platelet activation biomarker variation.

Platelet activation biomarkers Dabigatran (n = 33) Rivaroxaban (n = 72) p Value
ΔTAT 13.52 ± 4.17 2.04 ± 1.88 0.001*
ΔP-selectin 14.40 ± 2.16 4.79 ± 1.42 0.031*
ΔvWF 63.82 ± 11.95 19.57 ± 6.27 0.007*
ΔCD40L 30.88 ± 13.83 18.02 ± 9.23 0.543

Intraindividual plasma platelet activation biomarkers variation followed by 3-month post-anticoagulation with dabigatran or rivaroxaban. Δ referred to variation of platelet activation biomarkers; TAT, thrombin–antithrombin complex; vWF, von Willebrand disease.